Tracking of Tubular Molecules for Scientific Applications
click here to see the postscript version of this paper
In this paper, we present a
system for detection and tracking of tubular
molecules in images.
The automatic detection and characterization of the
shape, location, and motion of these molecules can enable
new laboratory protocols in several scientific disciplines.
The uniqueness of the proposed system is twofold:
at the macro level,
the novelty of the system lies in the integration of object localization
and tracking using geometric properties; at the micro level,
in the use of high and low level constraints
to model the detection and tracking subsystem.
The underlying philosophy for object detection is to
extract perceptually significant features from the
pixel level image, and then
use these high level cues to refine the precise boundaries.
In the case of tubular molecules,
the perceptually significant features are anti-parallel line
equivalently, their axis of symmetries.
The axis of symmetry infers a coarse
description of the object in terms of a bounding polygon.
The polygon then provides the necessary boundary condition
for the refinement process, which is based on dynamic
For tracking the object in a time sequence of images,
the refined contour is then projected onto each
Click here to see a movie of DNA tracking.